Job Description

Role Summary Lead end-to-end architecture and delivery governance for a regulated AWS platform supporting CDAP (pharmacometrics) and BEE (biostats). Own multi-environment architecture (DEV/TEST/PROD/DR) using Terraform modularization and GitOps practices. Define platform blueprint for compute, storage, networking, identity, CI/CD, observability, DR, and operational readiness.

Define target AWS architecture for VPC design with department isolation (subnets, NACLs, security groups). Architect Amazon EKS with namespace isolation (cdap/sas/gitlab) and Helm-based deployments. Architect AWS PCS (Slurm HPC) for NONMEM workloads including scaling and integration patterns. Architect storage layers using FSx NetApp ONTAP (NFS/SMB, multi-AZ) and FSx Lustre scratch for HPC. Define end-user access architecture using AWS WorkSpaces (Windows desktops) and integration touchpoints. Define data services architecture using RDS PostgreSQL and ElastiCache Redis for platform components. Design Identity & Access integration: Okta SSO + Duo MFA, AWS Managed AD, and RBAC/group strategy. Establish Infrastructure-as-Code standards: Terraform module strategy, remote state, environment variable files, and governance. Define GitOps standards: all Kubernetes manifests/Helm values in Git, CI/CD-driven promotion across environments. Define GitLab platform and pipeline strategy (runners, approvals, artifact management, reusable templates). Drive security-by-design: least privilege IAM, logging, encryption, secrets management patterns. Ensure regulated operations readiness: change control, audit readiness, validation documentation alignment (GxP/21 CFR Part 11). Define operational model: monitoring/alerting, patching cadence, backup/restore, DR runbooks, and service reporting. Create architecture deliverables: HLD/LLD, standards, reference patterns, runbooks, and handover package. Know R&D and FDA process - what we are building is tool for R&D team (to run simulation/analysis) who face FDA Audit, understanding of business and work closely with the business Work with stakeholders (client, engineering, ops) to manage risks, dependencies, and design decisions.

Expert level AWS architecture experience: networking, compute, storage, IAM/security, multi-AZ design. Expert level Terraform experience: module design, remote state (S3 + locking), multi-environment patterns. GitLab CI/CD pipelines: design, governance, reusable templates, runner strategy. Kubernetes/EKS architecture with Helm and GitOps workflows. Strong Experience integrating /connecting On-premises Active Directory to AWS. Experience with AWS HPC workloads. Strong experience operating platforms in regulated / compliance-driven environments. Strong documentation and architecture governance skills.

Have Healthcare/Pharma domain experience, with knowledge on FDA processes Experience working with business teams and R&D team with good understanding of business processes Experience with AWS PCS / Slurm. Experience with FSx NetApp ONTAP and FSx Lustre performance patterns. Experience with AWS WorkSpaces at scale. Experience designing/operating self-hosted GitLab in highly available setups. Experience with OpenKyber integration. Experience with Pharma domain an added advantage. Education / Certifications Bachelor's degree in Computer Science / IT or equivalent. Preferred AWS Solutions Architect Associate/Professional Certification.

For applications and inquiries, contact: hirings@openkyber.com

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